Severe Uncontrolled Diabetes & Diabetic Kidney Disease
Severe uncontrolled diabetes is one of the major causes of diabetic kidney disease (diabetic nephropathy). This condition commonly affects patients with long-standing poorly managed diabetes. Early evaluation by a specialist in kidney disease treatment is essential.
Common symptoms include:
- Swelling of the feet and ankles
- Puffiness around the eyes
- Shortness of breath while walking
- Frothy urine due to protein loss
Urine tests show proteinuria, which worsens blood pressure and increases serum creatinine levels. An elevated creatinine level indicates declining kidney function, making timely treatment crucial. Patients with uncontrolled diabetes should also get evaluated for diabetes-related hypertension.
How Severe Uncontrolled Diabetes Damages the Kidneys
High blood sugar damages the blood vessels inside the kidneys, leading to leakage of protein and progressive loss of kidney function. Patients often require ongoing evaluations such as kidney imaging tests, urine albumin tests, and blood investigations.
Treatment for Severe Uncontrolled Diabetes & Kidney Damage
- Strict blood sugar control (diet, tablets, or insulin)
- Blood pressure management
- RAAS blockade medicines (if clinically suitable)
- Limiting protein and salt intake
- Regular nephrology follow-up with a Kidney specialist for protein loss
Stages of Chronic Kidney Disease (CKD)
| CKD Stage | eGFR Level (ml/min/1.73 m²) |
|---|---|
| Stage 1 | ≥ 90 |
| Stage 2 | 60–89 |
| Stage 3 | 30–59 |
| Stage 4 | 15–29 |
| Stage 5 | < 15 |






